| Middle School | Location | Grade Span |
|---|---|---|
| Buist Academy for Advanced Studies | Charleston, SC 29401 | K-8 (Magnet School) |
| Charleston Charter School for Math and Science | Charleston, SC 29403 | 6-12 |
| Charleston Development Academy Public Charter School | Charleston, SC 29403 | PK-8 |
| Sanders Clyde Creative Arts Elementary School | Charleston, SC 29403 | PK-8 |
| Camp Road Middle School | Charleston, SC 29412 | 6-8 |
| C. E. Williams Middle School | Charleston, SC 29414 | 6-8 (Magnet School) |
| Montessori Community School | Charleston, SC 29414 | PK-8 |
| Pattinson's Academy | Charleston, SC 29414 | K-12 |
| Baptist Hill Middle/High School | Hollywood, SC 29449 | 6-12 |
| Haut Gap Middle School | Johns Island, SC 29455 | 5-8 (Magnet School) |
| East Cooper Montessori Charter School | Mt. Pleasant, SC 29464 | 1-8 |
| Laing Middle School of Science and Technology | Mt. Pleasant, SC 29464 | 6-8 (Magnet School) |
| Moultrie Middle School | Mt. Pleasant, SC 29464 | 6-8 |
| Thomas C. Cario Middle School | Mt. Pleasant, SC 29466 | 6-8 |
| Charleston County School of The Arts | North Charleston, SC 29405 | 6-12 |
| Military Magnet Academy | North Charleston, SC 29405 | 6-12 (Magnet School) |
| Morningside Middle School | North Charleston, SC 29504 | 6-8 |
| Malcolm C. Hursey Elementary School | North Charleston, SC 29406 | PK-8 |
| Jerry Zucker Middle School | North Charleston, SC 29418 | 6-8 (Magnet School) |
| Northwoods Middle School | North Charleston, SC 29420 | 6-8 |
| Deer Park Middle School | North Charleston, SC 29406 | 6 - 8 |
| James Simons Montessori School | Charleston, SC 29403 | Primary Montessori (ages 3, 4, and 5) - 8th |
| Simmons-Pinckney Middle School | Charleston, SC 29403-4742 | |
| Moultrie Middle School | Mount Pleasant, SC 29464 | 6-8 |
| Murray-LaSaine Montessori School | Charleston, SC 29412 | PK-8 |
| St. James Santee Elementary/Middle School | McClellanville, SC 29458-9422 | CD - 5 |
